SERVICES
DSEK (DESCEMET’S STRIPPING ENDOTHELIAL KERATOPLASTY)

What Is DSEK?

DSEK involves removing only the damaged endothelial layer and replacing it with a thin disc of donor endothelial cells along with a small amount of stromal tissue. Unlike full-thickness transplants, this technique preserves most of the patient’s cornea. The donor tissue is inserted through a small incision and positioned using an air bubble, which helps it adhere to the existing cornea. Only a few sutures are typically required.

Benefits of DSEK Surgery

Compared to full-thickness corneal transplants (PK), DSEK offers several advantages:

• Smaller Incision: Minimizes scarring and reduces the risk of complications.
• Faster Recovery: Vision often improves more quickly since most of the cornea remains intact.
• Lower Risk of Astigmatism: Reduced disruption of corneal shape, minimizing post-surgery visual distortion.
• Decreased Graft Rejection: The smaller graft size may lower the risk of rejection.
• Less Invasive: Faster procedure time and less discomfort during recovery.

Potential Limitations of DSEK

Despite its benefits, DSEK may not be suitable for everyone:

• It does not treat significant corneal scarring or outer layer damage.
• The donor graft can shift after surgery, potentially requiring repositioning.
• Patients must lie flat on their backs for 1–2 days post-surgery to help the graft adhere.
• Long-term outcomes are still being studied, as DSEK is a relatively newer procedure.
• Final vision may not be as sharp as with full-thickness transplants if scarring or irregularities persist.

Is DSEK Right for You?

DSEK is commonly recommended for conditions like Fuchs’ dystrophy, bullous keratopathy, and other endothelial disorders. Your ophthalmologist will assess your specific eye condition, overall health, and surgical goals to determine whether DSEK or another corneal transplant option is the best fit.